CNN Press Release - Christiane Amanpour today announced the guest line-up for her new interview show 'AMANPOUR.’ which debuts live on CNN International around the world on Tuesday September 21/22. Afghan President Hamid Karzai and U.S. Special Representative for Afghanistan and Pakistan Richard Holbrooke will discuss the issues underlying the powder keg that is Afghanistan -- the war there, the growing power of the Taliban, the fraud charges surrounding the recent election, and the tough road ahead.

Amanpour talks with two key players in a pivotal political drama that affects millions of people and that is grabbing world headlines.

“The impact of the situation in Afghanistan is felt far beyond its own borders,” said Amanpour. “It is emblematic of the type of issues I plan to tackle in this show. I want to dig deep into issues that stir the global conscience. I want to provide a forum for audiences to do the same. I hope to stimulate global dialogue about issues that deserve real debate, not just on public platforms but in the global living room.”

Over the next few weeks, Amanpour will also interview a range of political leaders, cultural icons and global influencers, to offer viewers a deeper examination of the major news stories and urgent issues around the world.

Among them are South African President Jacob Zuma; Former UK Prime Minister Tony Blair; Queen Rania of Jordan; Israeli Deputy PM and Minister of Justice Dan Meridor; Chief Palestinian Negotiator Saeb Erakat; former U.S. Secretary of State Madeleine Albright; Human Rights Council Report on Gaza War Richard Goldstone; and HRH Haakon and Mette-Marit, Crown Prince and Princess of Norway.

“This show is a global conversation on pressing issues of the day and how they affect people” said Amanpour. “As the show develops, we want to directly involve the audience to create a real-time global interaction that will add an exciting new facet to the power of the interview.”